TopoGEN provides innovative reagents and kits for topoisomerase research and mechanism-based drug development in cancer. Kits are available to assay for topoisomerases (I, II, IV and gyrase) and Tdp1, to measure topo/DNA interactions in vivo and to identify new topoisomerase drugs. TopoGEN also offer a complete line of DNA substrates topo inhibitors, antibodies, and kit replenishment reagents.

• Replacement components and topoisomerase inhibitors - for use with kits and research applications involving topoisomerases
• TopoGEN kits - assay kits, screening kits, precipitation kits, link kits, unwinding kits, immunofluorescence kits and immunoprecipitation kits
• Enzymes - sensitive to DNA quality
• Antibodies
• DNA - screened to support Topoisomerase (and gyrase) activity
• GeneFlash - to document and save your assay or cleavage data. This is tested and optimised specifically for use with TopoGEN assay and drug screening kits