Columbia Biosciences develops and manufactures purified antibodies, fluorescent markers and precision conjugates. These products increase diagnostic accuracy and therapeutic efficiency by improving sensitivity and reproducibility.

Columbia’s products have the advantage of being labelled with highly intense fluorophores derived from micro-algae. These fluorescent conjugates have traditionally been used for monitoring cell labelling using flow cytometry. However, with the large increase in the number of fluorescent imagers, new applications for these dyes have recently been developed for cell biology, fluorescence microscopy and protein detection; specifically a new simple and sensitive Western Blot test.

While other companies make and sell fluorescent labelled antibodies, Columbia has the distinct advantage of controlling the process from fluorescent dye production to the finished labelled antibody. Batch-to-batch variation is minimised, providing more confidence to researchers concerned with precision and false negatives.